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Image Search Results
Journal: Scientific Reports
Article Title: Mitigation of Tacrolimus-Associated Nephrotoxicity by PLGA Nanoparticulate Delivery Following Multiple Dosing to Mice while Maintaining its Immunosuppressive Activity
doi: 10.1038/s41598-020-63767-1
Figure Lengend Snippet: In vivo suppression of T cell proliferation in male mice following a daily subcutaneous injection (for 7 days) of either (1) Normal Saline, (2) Empty PLGA NPs, (3) Prograf, or (4) TAC-loaded PLGA NPs. Flow cytometry analysis was conducted on two cell groups: ( A ) CD4 + T cells and ( B ) CD8 + T cells (n = 6). The percentage of proliferating T cells is presented next to each gate. All samples are composed of the same number of acquired events (10 6 cells).
Article Snippet: Standard surface staining protocol was followed for CD4 + and CD8 + T cells using anti-mouse CD4–APC (R&D systems) and
Techniques: In Vivo, Injection, Saline, Flow Cytometry
Journal: Parasite
Article Title: Expression of TIGIT in splenic and circulatory T cells from mice acutely infected with Toxoplasma gondii
doi: 10.1051/parasite/2021010
Figure Lengend Snippet: Changes in TIGIT expression on T cells in different tissues after T. gondii infection. (A) Proportions of TIGIT + cells among CD4 + and CD8 + T cells in T. gondii- infected (RH) and normal mice (Nc) at 7 days after infection. (B) Results of statistical analysis of the percentage of TIGIT + cells among CD4 + T and CD8 + T cells in RH and Nc mice at 7 days after infection. (C) Dynamic changes in the percentages of TIGIT + in T cells at different time points. The results are representative of three independent experiments with five mice in each group per experiment, with data denoting means ± SDs.
Article Snippet: The antibodies used were as follows: anti-mouse Abs against CD3ε-APC-Vio770, mouse (Miltenyi Biotec, 130-117-676),
Techniques: Expressing, Infection
Journal: Parasite
Article Title: Expression of TIGIT in splenic and circulatory T cells from mice acutely infected with Toxoplasma gondii
doi: 10.1051/parasite/2021010
Figure Lengend Snippet: Changes in CD226 expression on T cells in different tissues after T. gondii infection. (A) Proportions of CD226 + cells among CD4 + T and CD8 + T cells in T. gondii- infected (RH) and normal mice (Nc) at 7 days after infection. (B) Results of statistical analysis of the percentage of CD226 + cells among CD4 + T and CD8 + T in RH and Nc mice at 7 days after infection. (C) Dynamic changes in the percentages of CD226 + T cells at different time points. The results are representative of three independent experiments with five mice in each group per experiment, with data denoting means ± SDs.
Article Snippet: The antibodies used were as follows: anti-mouse Abs against CD3ε-APC-Vio770, mouse (Miltenyi Biotec, 130-117-676),
Techniques: Expressing, Infection